I often found myself highlighting text, copying it, opening a browser, and paste it into Google to search for it. Quite a few steps for such a small job i recon. I still have to highlight the text i’m interested in, but afterwards a shortcut Ctrl + Win + G does the rest of the job. This little addition to my AutoHotkey file save me quite some time in the long run.
; Google search highlighted text ^#g:: Send, ^c Sleep 50 Run, http://www.google.com/search?q=%clipboard% Return
Related to this, i’ve also begun to use Ctrl + Win + W to look up things on Wikipedia.
; Wikipedia search highlighted text ^#w:: Send, ^c Sleep 50 Run, http://en.wikipedia.org/wiki/Special:Search?search=%clipboard%&go=Go Return
The same principle can be used for dictionary sites, Google Translate, searching eBay, and so on. The only limit is the keyboard.